Basil, the fourth century saint and theologian puts the predicament of religious knowledge this way: If you can't have certain knowledge of an ant, how can you expect to have certain knowledge of God?
"Let him expound the nature of the ant. Is its life sustained by breath and respiration? Is its body provided with bones? Is its framework braced with sinews and ligaments? Is the position of the sinews held secure by the covering of muscles and glands? Is the marrow stretched along the spinal vertebrae from the front of the head to the tail? Does it have a liver and a gall bladder near the liver; also kidneys, a heart, arteries and veins, membranes and cartilage? Is it hairless or covered with hair? Has it an uncloven hoof, or feet divided into toes? How long does it live? What is the manner of reproduction?...
Let him who boasts of the knowledge of things existing explain the nature of the ant...But, if you have not yet, by your investigation, understood the nature of the smallest ant, how can you boast that the incomprehensible power of God is clear to your mind?"
Ok, so we've advanced significantly in our understanding of the ant. But what of God? Is he any less inexplicable, regardless of our advance in knowledge of things tangible?